Mental
Health
Mental health challenges are increasingly recognized as a global crisis, profoundly impacting individuals and communities. Yet, systems to support mental health are often fragmented, under-resourced, and difficult to navigate. For young people especially, untreated issues like anxiety and depression can be life-altering, affecting not just their immediate well-being but their ability to thrive long-term.
At Greenbridge, we see immense potential to address these challenges early—before they escalate into crises. By focusing on prevention and early-stage interventions, we aim to equip young people with the tools, skills, and resources they need to navigate mental health challenges as they arise.
We support organizations delivering accessible, evidence-based solutions that integrate mental health care into schools, communities, and other early touchpoints in young people’s lives. By breaking down stigma and barriers to care, we hope to foster a healthier, more resilient generation, better equipped to navigate life’s challenges. This is a complex issue, but every step forward unlocks new opportunities for young people to access the mental health support they deserve.
Grantees
Meet the incredible organizations that we are supporting. Each is creating a meaningful impact in its own way. We hope you will spend time learning more about the ones that speak to you.
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Koko provides mental health support directly within the platforms where young people are already spending their time—like Discord, Twitch, and Instagram. Through guided journaling, single-session tools, and peer-supported responses, Koko delivers scalable, evidence-based interventions in real time. Their approach creates a safer digital environment where youth can access meaningful support the moment they need it.
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We’re excited about what Rob and his team are building to meet young people where they are—both emotionally and digitally. Koko’s interventions are not only accessible, but also rigorously evaluated, with promising third-party assessments of their single-session tools. We’re particularly drawn to their Mental Health First Aid training for youth, which equips young people to support their peers—recognizing that many turn to friends first when struggling.
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Inseparable envisions a world where mental health is treated as a critical and equal piece of overall health, and where systems are designed with their impact on mental health in mind.
Inseparable is a smart and effective agent for change, utilizing a campaign-style approach that results in fast and meaningful progress.
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We are proud to support Inseparable, led by the dynamic Bill Smith, who is leveraging best practices from other successful movements to drive tangible progress in mental health support. Inseparable’s innovative approach is creating real, lasting change in how mental health care is accessed and delivered. We are particularly excited about Sarah Broome’s initiative, which is unlocking Medicaid dollars to bring essential mental health resources directly into schools, ensuring that students receive the care they need right where they are.
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Upstream Education provides bite-sized, evidence-based mental health tools designed to fit seamlessly into K–12 classrooms. By equipping educators with short, 10-minute digital lessons and practical strategies, Upstream helps students reduce anxiety, build emotional resilience, and practice essential life skills. Their proactive approach seamlessly integrates mental health into daily routines, creating supportive classroom environments where students can thrive both emotionally and academically.
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We are excited by Tessa and her team’s ability to bridge digital mental health tools with everyday classroom life. Upstream empowers educators with accessible, plug-and-play resources that make actionable mental health support a natural part of the school day. We are excited to see the transformative impact their approach has on student life—fostering resilience, building confidence, and strengthening classroom culture from the ground up.
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One Mind catalyzes visionary change through science, business, and media to transform the world’s mental health.
The One Mind Accelerator backs visionary founders of early-stage startups with the network, education, and capital to rapidly build category-defining companies that improve the lives of people living with mental illness.
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We chose to support One Mind for their groundbreaking work in advancing mental health research and treatments, and we’re particularly excited about their accelerator program, which fosters the next generation of innovators. This initiative aligns with our commitment to supporting early interventions that can make a transformative impact on mental health outcomes, especially for young people.
Mental Health-
Focused
Investments
Here are some of the exciting firms leading innovation to tackle critical challenges in mental health.
GreyMatter helps founders navigate the complex mental health startup journey.
The One Mind Catalyst Fund invests in graduates of the One Mind Accelerator to help them scale their solutions and impact people living with mental illness.
Ophelia’s mission is to make evidence-based addiction treatment accessible to everyone.
PsyMed Ventures funds and supports founders revolutionizing brain and mental health through innovative neuroscience and frontier technologies. Their founders align healing, responsibility, and profitability.